pentobarbital will reduce the level or outcome of nateglinide by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Observe.
Check Closely (one)pentobarbital will decrease the extent or influence of benzhydrocodone/acetaminophen by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Caution when discontinuing CYP3A4 inducers which are coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone could improve and can lead to probably deadly respiratory melancholy.
pentobarbital will decrease the extent or result of buprenorphine, extended-acting injection by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Clients who transfer to buprenorphine prolonged-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers needs to be monitored to make sure buprenorphine plasma levels are suitable.
pentobarbital will minimize the extent or influence of estrogens esterified by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will decrease the level or influence of repaglinide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Pentobarbital administration is through IM, IV, or oral routes. For IM administration, injecting no more info more than five mL and only into a considerable muscle to prevent tissue discomfort or necrosis is recommended.
pentobarbital will lessen the level or impact of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the level or impact of ambrisentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Mysterious.
pentobarbital will lessen the level or effect of carbamazepine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital decreases amounts of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unidentified.
pentobarbital will lessen the level or influence of pitolisant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Pitolisant exposure is decreased by 50% if coadministered with powerful CYP3A4 inducers.
pentobarbital will minimize the extent or result of tolterodine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will decrease the level or influence of avanafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. For patients with ED, watch reaction thoroughly as a result of probable for lessened performance.
pentobarbital will lower the level or influence of ramelteon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.